organizations, Gurumayi took over the guru lineage of Siddha Yoga. Her lively brother’s worldly preoccupations with jazz drumming and confessions of promiscuity led to his giving up of the orange robe of the denunciate, sanyasi, for the blue robe of worldliness, exchanging one kind of energy for another. Brad Gooch who visited Gurumayi’s Ashram in Ganeshpuri, India, wrote in his recent book, Godtalk, that she looks like a “synthesis of Indira Gandhi and Bianca Jagger.” In what reads like a Hunter Thompson episode in an unwritten book called Fear and Loathing Along the Guru Trail, Godtalk’s explication of Siddha Yoga was dominated by yellow journalistic rumors such as the one about Baba’s use of a gynecologist’s table with stirrups for non-ejaculatory Tantric practice with some female followers. This unconfirmed claim remains, as Gooch says, in the realm of “…he said, she said.” Gooch’s exploration almost ignores the deeper meanings of Kashmir Shavism, Buddhism and Kundalini Yoga that compose the philosophical foundations of Siddha Yoga. The importance of knowing, loving and becoming one with the God within trivializes all but ungenerous or hurtful interpersonal behavior. Even the tougher version of the Ten Commandments in Leviticus 19 would not necessarily disagree. When a Los Angeles Times reporter tried to chide Baba about being driven about in his “worldly” Mercedes sedan, he explained that a very wealthy Indian merchant had given it to him and “…I have to put my behind somewhere.” Similarly, why would Gooch’s account of Baba’s Tantric practice, even if true, ruin the imago of him in my mind unless I had already surrendered to the pantheon of good and evil absolutes of Judeo-Christian taboo? My knowledge of these non-materialistic meanings of apparent materialism began with one of the favorite finds of Baba’s youthful days of guru hunting: Zipruanna, who, wearing only a loincloth spent all day, every day, on a stool in the middle of a garbage dump. Remarkable changes occurred in people who spent time there in his presence. Baba said the identity of guru was established by the results experienced by those that spent time in his presence. It could not be defined by the physical features or ritual conduct of the 48 interaction. People become spiritually energized and change in Zipruanna’s smelly, garbage-filled presence. I keep a picture of him on my desk. Gooch, in his implicitly and superficially righteous preoccupation with what he considered disenfranchising human vulnerability, recalls how the medieval church used the difficult to impossible vow of chastity for political control of their priesthood. He seemed to have missed Baba’s lessons about the remarkably simple sounding practices for mobilizing the energy of the God-receptive state. Once in this new state, the rest of the metaphysical work almost takes care of itself. I, like many others, adopted Baba’s mantra, Om Namah Shivaya, “I worship the God within me (and you)” that he was given by his guru. The inner chant of this mantra brings me to an internal quiet in which things become clearer. Meditation, chanting and service to the guru was motivated by his promise that my egoistic concerns ranging from the number of publications on my curriculum vitae, to the size and adroitness of my penis, would disappear autonomously in the Baba state of bliss. This sounds very much like the role of the transition to an “active intellect.” in Abraham Abulafia’s 13 th Century Commentary on the Secrets. Arduous study of the spiritually dense writings of Sri Aurobindo during the days with Professor Spiegelberg at Stanford gave me a peak into the simple but difficult to execute idea of “simply” becoming the transcendently comprehending state of existence-consciousness-bliss. Whereas Baba would occasionally lapse into terse Sanskrit verse and its multiplicity of potential meanings, Gurumayi keeps things simple. Sitting silently and immobile at satsang for hours, she radiates transformational energy, shakti, that makes ruminations about human affairs seem unimportant. The work is about getting the self concerned head noise of ones preoccupations sufficiently out of the way to allow the discovery of the God who has been waiting patiently within. A fellow ashramite gave me a photograph of my first audience with Gurymayi. It showed me on my knees in front of her. She appears to be dismissing me with a baleful, almost disdainful look as my introducer, gesturing broadly, was, unasked, reciting a list of my professional bona fides. The picture caught her waving me off with a long, peacock-feathered stick. Obviously unimpressed, she is sending me back to my all night, every night, tent cleaning labors at the Ashram. Rich Indian 49 businessmen, whose large donations were a major source of support of the Ashrams, faired little better. They seldom received a personal audience or favorable seating at Darshan, the evening public time of question and answers with the guru. In contrast with the relatively easy public availability, mischievous play, provocative humor and worldly sophistication of Baba, the ambience of Gurumayi is more private, simple, serious and subtle. It is as powerful, but in another way. In response to Gurumayi’s ascension to Siddha Yoga’s singular guru, I imagined hearing Baba saying that God energy was at least androgynous, if the dimension of sexual identity was relevant at all. Baba taught that divine energy, by necessity, is expressed through a wide variety of particular personalities and cultures and should not be confused with the details of its manifestations. This included the sexual identity of the chosen Vehicle. Guramayi’s central theme, as I understand it, concerns the simple, quiet and pervasive powers of love and faith. Some say Baba took the path, marga, of selfless action, karma-marga, whereas Gurumayi took the bhakti-marga, the road of loving devotion and faith. The third marga is jnana-marga, my inclination, is the road of intellectual study and knowledge. Aldous Huxley related the choice among these three categories of yoga practice, to the physical and personality types of William Sheldon’s 1954 Atlas of Man. Karma yoga corresponded to the mesomorphic body type and the assertive boldness, high energy, and interpersonal callousness of the somatotonic personality. Bhakti Yoga was the characteristic choice of endomorphic body types with the viscerotonic personality traits of sociability, good will, tolerance and love. Huxley associated Jnana Yoga with ectomorphic body type and the cerebrotonic characteristic of shyness, sensitivity and intellectuality. My summers with Baba at his temporary Ashram in Venice, California and the permanent American Ashram in South Fallsburg, New York, were spent in daily, very early morning, chanting of the gurugita after most of the night spent taking down, cleaning and putting up large tarpaulin meeting tents. I was assigned this simple, arduously manual, all night work after being interviewed and found out to be a professor and chairperson of a medical school department. Baba instructed his assignment committee that many if not all professorial egos would benefit from what 50 Andrew Carnegie famously called the dignity of real work. Spicy one dish vegetarian meals, twice a day meditation and brief stolen naps consumed the rest of the day. I found myself meditating for longer and longer times, chasing the promised Blue Pearl that Baba said appeared behind the eyes near the supreme meditative end point. Beside care with the titration of meditation-induced interpersonal disconnection, detachment with love is the desired end point of most Hindu and Buddhist meditative practice, another set of “side effects” of the energy arising early in the course of too much meditation is called kriyas, spontaneous episodes of involuntary behaviors and postures of the body such as unprovoked chanting and writhing and stereotyped hand positions called mudras. Baba told us one of his kriyas took the form of spontaneous erections that occurred during his first experiences with deep meditative states. I recall a woman physician and fellow ashramite in Los Angeles telling me that her panties often got so soaked during meditation that she worried about being stuck to her cushion. Beyond these initial somatic overflows of Divine Energy, shakti, emerges a vision of the Blue Pearl, bindu, Baba’s “gift from the Goddess Kundalini.” As he entered this stage, he said that his mind filled with “joyous contentment.” Jewish mysticism of the 1300’s acknowledged the neighborhood relations of Eros and the Sacred. More formal and scientific uses of the word, energy, like all objects of thought embeddable in a mathematical context, are abstract and relational. In his book, Mathematics-The Music of Reason, Jean Dieudonne′ treats mathematical objects as objects of thought. Dieudonne′’s book documents the 19 th Century transition from concrete, visualizable, classical mathematics to abstract, nonvisualizable relational ideas. This conceptual transition to abstract, relational thought objects that are no longer representable by pictures or accessible to our senses of mathematics and physics is yet to reach the concrete DNA-causal religionists of modern molecular biology. In 20 th Century mathematics, Dieudonne′ observes that “…the primary role in theory is played by the relations between mathematical objects concerned rather than the nature of the objects themselves…these relations are often the same for objects which appear to be very different and therefore they must 51 be expressed in ways which do not take these appearances into account…and can be specialized at will…” DNA sequences are, as MIT molecular biologist, Eric Lander observed, nothing more than an elementary “…list of parts…” In fact, since about 1% of the nucleotides are relevant to functional genes, one might say that the important members of this list of parts are distributed very thinly among many more apparently unimportant ones. The next frontier will certainly involve an understanding of the dynamics of the interactions among elemental parts and in more abstract laws about molecular biological relations; a focus on the dynamics, not the structural parts, that regulate and control their expression. * * * I made a pilgrimage to spend eighteen months within Rene’ Thom’s penumbra, living among mathematicians in his “ashram” in Bures sur Y’vette, France. Thom was one of the founders of the Institute des Hautes D’Etudes, IHES, Institute for Advanced Scientific Studies, created to stanch the flow of high-level scientific talent away from France after the Second World War. It is in Bures sur Y’vette, deep in a green forested valley, 50 or so miles South of Paris, in a building packed with small, thin walled, big windows-on-the-woods offices. Each office contained a single hard chair, an old office desk, two walls of blackboards and a box of white only chalk. The use of colored chalk was felt to be without mathematical rigor because its use substitutes colors as dimensional descriptors for more demanding abstract and formal representations. Color was cheating. Meditation in this ashram was practiced by staring, pacing, scribbling, and humming, mumbling, belching and farting through the Institute’s thin office walls. The building, though almost completely occupied, was otherwise silent. The Institute was populated by such world-class mathematicians and theoretical physicists that once inside that building, I felt so intimidated that I almost never spoke above a whisper. Listening to excellent William Thurston’s casual use of a tiled bathroom floor to motivate a unique partition of a topological space, I was attacked by the awe of an early morning visit to an almost empty Notre Dame Cathedral in Paris or standing in front of Michelangelo’s radiant marble statue of Mary and Jesus the Infant in the Vatican. 52 Though the environment was one of tranquil academic scholarship, I lived charged with anticipated performance anxiety about the seminars on the brain as a dynamical system I was scheduled to present to these (I feared) ready-to-bedisdainful, prize-winning, pure mathematicians and theoretical physicists. My dorm-style sleeping room at IHES was, in winter, painfully cold and drafty; the narrow iron bed’s thin mattress contained lumps of persistently disturbing dreams, the small scratched table for work shim-irreparably wobbled. A faded poster of Van Gogh’s garden was tacked crookedly on the door facing the toilet in the dank, dimly lit small bathroom. A dwelling for distracted young mathematicians. A retired but still famous Parisian chef cooked many course, elegant meals every afternoon. The food was accompanied by so many liters of unlabeled red wine and peer pressure to be French and socially drink it that it became a choice between dulled, blunted,. sleepy post-prandial afternoons or living on bread, many cheeses, apples and Perrier water, alone in my room. I chose the latter. Thom’s gifts to us theoretically oriented non-mathematicians were diagrammatic, easy-to-visualize pictures that allow the intuitive capture of counterintuitive discontinuities in functions. How we might imagine that a smooth and continuous change in a cause of something can lead to a big, discontinuous change in the results. His system of topological (shape not size) diagrams was useful when considering up to four causal variables and one to two dependent variables that described how things behaved. For an important real life example, in modern clinical pharmacology, the smooth dose-response curve consistent with the physician’s intuition that if a little drug didn’t work, a little more may do so, should become an up and down search for the dose-region for the desired effect which may involve a lower amount than a previously ineffective drug dose. The therapeutic effect may occur in the middle of a narrow dose range with too much or no effect occurring out of this span. In many physical systems, sudden and global transitions in state, from incoherent light rays to coherent lasing and from laminar flow of fluids to turbulence, emerge unexpectedly when causal parameter are moved into what some call the critical region of the values of control parameters. Outside this region, cause and result 53 were behaving linearly and smoothly whereas within this region we observe global and dramatic changes via a forced discontinuity in what Thom called a catastrophe and others use related words such as bifurcation or phase transition. The transitions from painful fatigue to running rage and then to ecstatic transcendence feels like the gifts from two kinds of Gods, the first, bearing the righteous lawfulness of the Old Testament, the second bringing the empathic forgiveness of the New Testament Jesus. Catastrophe and bifurcation theories predict and keep track of these transitions using mathematically describable changes in global characteristics of the “motion” using technical descriptors such as eigenvalues, germs and jets. Thom taught me my first catastrophe, called the cusp, in words during our late afternoon walks along a shadowed green wooded path on the grounds of the Institute des Hautes Etudes, outside of Paris. My homework consisted of trying to visualize his verbal descriptions. It was not until weeks later that he drew the geometric object being discussed on the blackboard. With eyes twinkling and in his provocatively playful style, he said, “Imagine an empty rectangular box with the front edge of its roof buckled into an `S’ and the back edge, an unfolded, left-to-right gradually rising simple smooth curve. If one moves the causal force from low to high, from left to right along the back of the box, the changing effect (represented by height) would be smooth; moving from left to right in the front encounters a sudden drop off at the S shaped buckling, a discontinuity in roof height indicating a discontinuity in effect. The energy equivalent height of the roof graphically indicates the amount of result. The roof is the manifold upon which the result of causal change is portrayed. The two dimensional floor of the box represents a graph of the two causal parameters, the increasing amount of normal factor going left to right along the `x’ dimension, the increasing amount of splitting factor (taking one from the back to the front to the region of the buckling) going back to front along the `y’ dimension.” He gave me some examples of systems that showed cataclysmic changes in effect from smooth changes of normal and splitting factors. About the onset of a war: “At the back of the top surface of the box, the manifold, the normal factor increasing from left to right is the amount of the perceived threat. The splitting factor 54 decreasing from front to back is the cost (and ability to pay) for war. Without the financial capacity to make war, threat goes from left to right smoothly at the back of the box as tension gradually increases without the onset of armed conflict. When effective fighting capacity is cheap and/or already well funded, the country well armed, the increases in threat go from left to right at the front edge of the box and encounter the cliff of catastrophe and war is declared. Cost of, or ability to wage war varies from the front to back, and serves as the splitting factor. Considering prison riots, social tension is the normal factor and alienation (degree of identification with prison authority) is the splitting factor.” Using factial expressions of dogs sketched by the Konrad Lorenz, Christopher Zeeman then of Warwick Mathematics Institute in England, considered countenances reflecting increasing rage as the normal factor, the amount of fear was the splitting factor. Increasing rage at high fear increased smoothly at the back of the box; at low fear, increasing rage falls off the cliff to an animal attack at the front of the box.” He paced as he talked, occasionally looking up to see if I was following him. He continued, “A light above the box casts a shadow from the roof to the floor, outlining the gradually widening fold created by the transition from the smoothly rising back of the roof to its `S-shaped’ front. This triangle on the x-y causal floor is the region in which the discontinuity in the result surface roof results and is called the bifurcation set. An increasing amount of the causal `normal factor’ is represented from left to right along the `x’ dimension, the results of which change smoothly at the back of the roof but encounter a discontinuous jump up or fall down crossing the inaccessible crevice in the `S’ fold at the front of the roof. Again, the triangular shadow on the floor made by the fold indicates the parameter region in which discontinuous changes in the result surface occur. The reason the parameter that determines the front to back location of the left to right movement of the `normal factor’ is called the `splitting factor’ becomes obvious. Its value determines whether the results induced by increasing amounts of `normal factor’ will be smoothly changing or generate a discontinuous jump. The entire visualizable object is called a cusp catastrophe and it along with higher dimensional parameter region-inspired shapes such as the 55 swallowtail and butterfly buy back the smooth DE deterministic intuition lost with discontinuous changes in results.” He grinned mischievously as he asked, “Can you see it?” Thom’s catastrophes serve as accessible and powerful theoretical settings for the use of energy as a generalizable, one dimensional, dependent, resulting effect, influenced by one or several, sometimes conflicting, independent, causal, variables. For more examples: the weight of a ship (smaller to greater, left to right, along the x, normal dimension) and the position of center of gravity (smaller to greater, front to back, along the y splitting dimension) are causal with a jump in roofheight energy from stability to capsizing, a discontinuity emerging from initially smooth changes in stability. As above, gradually increasing tension (the left to right normal factor) and alienation (the back to front (splitting factor) in inmates generate a sudden increment in energy, from subtlety increasing tension in relative quiet to the sudden outbreak in a riot in the prison population. Embryological notochord somitogenesis, (that which become the vertebrate of the spinal column) has a smooth (left to right) causal influence that Chris Zeeman named a normal factor. It is the smooth growth of the material wave of mesodermal (to become muscle, connective tissue and bone) tissue. Zeeman called the front to back dimensional gradient of influence, the secondary wave of adhesiveness, the splitting factor. The value of this secondary wave co-determined a critical-valued interaction between these causal parameters leading to a discontinuous change in the “energy” equivalent continuity of developmental growth and vertebral column segmentation. A little more technically: Thom’s basic mathematical contributions were in differential topology and analysis with particular emphasis on what is called structural stability of surfaces representing and supporting actions called manifolds. For example, in a graph of a function, say F(x), such that a change in cause x determines what happens to the result y= F(x), the stability question involves what happens when one perturbs F(x) with a littleδ, i.e. δ + F(x). Do the topological properties of the surface representing the potential range of actions of the system (such as nearness of an originally close point set, continuity and connectedness of the surface, its dimensionality, its compactness as a generalization of finiteness) 56 remain the same after perturbation? Note that the inter-data point metric distances are not considered. If they do, the two dynamical objects being compared are topologically equivalent. The test of this equivalence requires the mapping one set onto the other with, at most, smooth distortions of either or both surfaces. In the context of catastrophe-related bifurcation theory, if a δ converts a steady valued fixed point to an oscillating cycle on a manifold of potential actions, also called a state space, then the fixed point system was not structurally stable. In phase space, this is seen as a change-in-causal-parameter induced transformation of a dot to a circle. If the one frequency circle is perturbed to a manifold of the system’s actions consisting of two independent frequencies, the circle takes the topological form of the crust of a doughnut, one frequency graphed spiral winding around the doughnut, the other winding along the doughnut around its orifice, the circle is not structurally stable. If δ distorts the frequency-amplitude relations on a surface such that the manifold of possible actions is distorted from a doughnut to a tea cup, both topological manifolds being one holed surfaces and therefore topologically equivalent, the system is structurally stable. Perturbed systems that maintain the sequence of points in time in sequential order (though the distances between the points may be different), are generally structurally stable. The seductive possibility, one which Thom realized so successfully, was that in the language of distance-independent differential topological forms, there would exist a small, finite set of shapes categorically describing the causes and result parameter spaces from which, even without specific quantities, universal qualitative (including discontinuous) behavior could be described and sometimes predicted. A formal yet general categorical system within which a small set of universal discontinuous changes in global qualities could be rationalized seemed seductively applicable to the enlightenment transitions, spiritual transformations, appearing suddenly after months and years of disciplined spiritual practice. The Platonic view is that the universal forms of discontinuous change existed before they could be about anything specific, before the universe was born. In this era of nonlinear dynamics and dynamical system, common dynamical scenarios give accounts of smooth changes in causes leading to discontinuous 57 changes in results. The Nobel Prize winning solid-state physicist, Phillip Anderson, in a short but memorable piece in Science in the 1970’s said it tersely, “More is different.” This general, qualitative mathematical theory of discontinuous change models nicely the sudden delivery of the first and second second winds from gradually and continuously increasing running distances as well as the abrupt transmission of the guru’s “energy”, shaktipat, from smoothly increasing amounts of chanting, meditation, guru service and Baba love. Gradually changing forces leading to sudden changes in an energy-equivalent result are found in most rigorous form in Rene′ Thom’s singularity-bifurcation-catastrophe theory applied to rational mechanics and geometric optics. Here the existence of already solvable computational formalisms makes this more qualitative approach superfluous. On the other hand, the power of this both basic and applied mathematical orientation and method lies in its approach to the qualitative understanding of variously induced global and sudden changes in an energy-equivalent observable in biological, psychological, spiritual and social systems, fields of study in which little abstract and formal lawfulness presently exists. Oxford’s Chris Zeeman’s more accessible applications of Thom’s deeper, more generally ramifying, almost mystical (due to their apparent wide generality) results, include approaches to real world problems such those above as well as the sudden change in excitable membrane potential accompanying the generation of the heart beat and neuronal discharge; mechanisms of opinion change, stock market crashes and, as noted above, the social science of riots. Whereas Thom’s On Structural Stability and Morphogenesis can be said to be scriptural, Zeeman’s Selected Papers, 1972-1977 constitute the Book of Common Prayer of this church. To review and place catastrophe and bifurcation theories in the context of the differential equations of mathematical physics and biology, causal determinism implied by differential equations conventionally requires continuity and smoothness in behavior to be credible. Our intuitions as well as the formal conditions for the generic differential equations of mathematics and physics imply that smoothly increasing amounts of cause lead to smoothly increasing results and yield at least local predictability: a little more leads to a little more, a little less leads to a little less. 58 This smoothness-dependent intuition of determinism breaks down in nonlinear equations as well as in a wide variety of the machines of experimental physics, from the sudden coherent lasing of previously incoherent light to the vortices and turbulence in suitably bounded rotating or flowing fluid. It took me a while for these topological still shots and movies of the head to become real. Nevertheless, the enrichment of intuition was well worth it. Of course one could smoothly increase the normal factor weight of a ship until it gradually sank, but if one moved the center of gravity splitting factor to an eccentric position in the ship in the parameter region of the bifurcation set, a sudden global capsize before weight-induced gradual sinking made sense. I could see it. Indeed, increasing normal factor tension in a prison population that was identified, not alienated, from the officials and mores of the penal institution, would increase social symptomotology gradually. However, increasing the splitting factor of social and institutional alienation results in the cataclysmic change of a riot with increasing tension. I could see it. Do we need to know the causal equations to anticipate instability and discontinuity in our lives? Zeeman making Thom’s thoughts accessible to us plain mortals said no. He suggested that we could use several diagnostic phenomenological signs to make a good guess about whether we are near or within the bifurcation set. Depending upon the route that the causal variables take through the shadow of the bifurcation set, we may see very large fluctuations in our observable. The Dow or S&P stock indices in the neighborhood of a sudden large change is often presaged, sometimes for weeks, by a marked increase in volatility, fluctuations between extreme values. Theorists call the statistical properties of a time series of values behaving this way anomalous variance. For several months, I did psychotherapy with a genuinely spiritual Catholic priest who only some Sundays served the Eucharist, the corporal presence of our Lord at Communion, wearing no trousers or underpants beneath his robes. A sudden change in a stock index in response to the “shock” of a terrorist attack takes much longer to settle down if a cataclysmically bigger change is in the neighborhood. This extension of the system’s usual relaxation time is sometimes called critical slowing. In the bifurcation 59 regime of a schizophrenic break down, critical slowing can be both global and literal as the patient freezes in catatonic postures. In the neighborhood of the bifurcation set, big jumps in the stock index, up or down, are possible under almost the same surrounding conditions. This stock analyst-humbling phenomenon is called bimodality. Jimmy Swaggert’s Saturdays were often spent watching the show at naked dance parlors and buying videos at the pornography shops of Metairie Highway near Schwegmann’s Grocery outside New Orleans. Sundays found him on national television engaged with infectiously real, transcendent experiences in the public arena of the pulpit. The ecstatic congregation was deeply moved by his eloquent and tearful sermons about sin and salvation. Counter to most suspicions, this is less conscious fakery than the genuinely felt alternating states intrinsic to the bimodality in neighborhoods of spiritually unstable, born again transitions. Similarly, beginning with nearly the same initial values near the boundary of the bifurcation set, very similar motions lead to dramatically different results. This counter-intuitive behavior has been called divergence. At UCLA’s Neuropsychiatric Institute, I interviewed a pair of lively teenage, genetically identical male twins raised by a loving family in Los Angeles’s Valley. One was president of his high school class, a Sunday school nursery school volunteer and a Saturday soup server to the poor. The other twin sold pot and cocaine to support his habit. Deep and potentially dark mysteries live in these spiritual bifurcation sets. They leave us pondering child sexual abuse by deeply religious clergy and the massacre by mass suicide of a New Christian congregation by James Jones. We wonder why it is that fundamentalists (Jewish, Christian and Muslim) have the most ecstatic and direct validating experiences of God and do the most shooting and bombing of other people. In Burt Lancaster’s portrayal of bifurcation set dweller, Elmer Gantry, charismatic believer and exploitative psychopath, were simultaneous and both credibly real. Another feature of the occupancy of this bifurcation region in control space is that the values producing a sudden jump that occur passing through going one way along the “normal” dimension usually jump back much further along when moving 60 the other way. Theorists call this characteristic sign of bifurcation land, hysteresis. It is generally known that sudden healing changes of the first born again experience can arrive magically fast whereas a run at it a second time, another born again state after the loss of the first one, comes, if at all, with much more effort and difficulty. Members of Alcoholic’s Anonymous know that getting on the AA wagon the first time may be quick, joyful and easy. Getting back on this wagon after a fall is much more painfully slow and demanding, analogous to the Carmalite monk; St. John’s lost faith engendered suffering of the Dark Night of the Soul. Viewing the instabilities and extremes near the boundary of a bifurcation brings inquiries and advice about why a rational compromise, some form of disciplined moderation, would not be more desirable. It turns out that in this parameter regime, the in-between state is intrinsically inaccessible. The pocket in the S shaped fold of the upper manifold cannot be attained, at least for very long, by varying the values of the two parameters. However, if one increases the number of controls, it might be possible to stabilize a small island in a parametric sea of instabilities. In an application of this strategy, Smith College and Harvard Professors James Callahan and Jerome Sashin used a geometric representation of the difficult to stabilize region of normal weight on a double cusp manifold representing the behaviors of patients with eating disorders with both anorexia nervosa and bulimia. They varied five controls to stabilize a very small result area representing normal eating by varying the control values for ability to verbalize feelings, to imagine solutions, to defend against anxiety with unconscious forgetting called repression, to make contact with realistic rationality and to modulate feelings with say exercise, meditative practice or psychopharmaceuticals. My experiences with the so-called borderline personality, with the tendency toward sudden and global personality change, from Sunday school teacher to Harlot in the space of a breath, has been both sexually exciting and personally ruinous for me in my life. I could feel the instabilities in these dwellers of the bifurcation pockets and my heart raced at the promise of mutually unconsidered impulses, the blurring of orificial identities, the experiments with sexual roles and modes and the incipiency of collapse into regressive mud play. Most of all, I anticipated that their 61 screaming orgasms, potentiated by a natural inclination to bifurcate, would be so messianic as to carry me along to a transcendentally erotic new place. Unfortunately, paranoid rages, bursts of promiscuity and hopeless inconsistency of goals and efforts dominated the remainder of our living days. Further Readings for TRANSMOGRIFICATIONS OF ENERGIES Religions in Four Dimensions; Existential, Aesthetic, Historical, Comparative, Walter Kaufman, Reader’s Digest Press, 1976 Religious and Spiritual Groups in Modern America, Robert S. Ellwood, Prentice- Hall, Englewood Cliffs, 1973. The Evangelicals, What They Believe, Who They Are, Where They are Changing, David F. Wells and John D. Woodbridge, Abington Press, Nashville, 1975 A Nation of Believers, Martin Marty, Univ. Chicago Press, Chicago, 1976 Conversion: Christian and Non-Christian, Alfred C. Underwood, George Allen, Unwin Ltd., London, 1925 Eros and the Sacred, Paul Avis, SPCK, London, 1989 Mukteshwari, The Way of Muktananda, SYDA Foundation, Ganeshpuri, India, 1972 Godtalk, Travels in Spiritual America, Brad Gooch, Knopf, N.Y. 2002 The Beat of a Different Drum; The Life and Science of Richard Feynman, Jadish Mehra, Clarendon Press, Oxford, 1994 62 The Shape of Space, Jeffrey Weeks, Dekker, NY, 1985 The Topological Picture Book, George K. Francis, Springer-Verlag, NY 1988 Mathematical Models of Morphogenesis, Rene Thom, Wiley, NY 1983 Catastrophe Theory, Selected Papers, 1972-1977, Christopher Zeeman, Addison- Wesley Reading, MA 1977 63 CHAPTER 4: SENSUAL IN-BETWEEN ENTROPIES Since the early teens, I’ve been beguiled by girls and women that have what might be regarded as exquisite sensibility, perhaps more precisely, exquisite self sensibility. These inhabitants of the near transformational neighborhoods of bifurcation sets, are grandly responsive receivers of emotionally significant information arising from their insides and the world. They are the canaries in the deep mines of human experience. Not the usual one lively-eye, one sober-eye, binocular difference of most of us, both their eyes sparkle, their feeling antennae await a happening and each is regarded as new. I spot these brains in a crowd within minutes and am compulsively drawn to know them better, to become part of them, to vicariously experience and serve them. They seem to have little inhibitory control of even weak sensory information on its way to their strong, global feelings. Near ecstasy and excruciating pain await. They feel their anticipations with their body, down to their painted toes. Their receptivity brings me lower abdominal warmth in remembrance. At sixteen in my Dad-purchased second hand Ford convertible, I was parked with my new girl friend on Sarasota’s Lido Beach, hearing and seeing dark shadows of the Gulf of Mexico’s waves hit white sand against the night sky. I took her flat party shoes off to message her feet. When I kissed her left foot and sucked gently on her toes, she gasped and became faint. She told me that a strong electric shock 64 had run up her back. The passionate licking and sucking of her musky, moist, pink labial lips brought what she said were explosions of pink and blue lights. She had several ecstatic multicolored crises in a row, sometimes without pause. She begged me to stop. I was as pleased as a sexually inexperienced young man in love could have possibly been. Bowled over by what seemed to be the uniquely sensual properties of her brain, I began to wonder if her sensitivity was more general when she asked me to keep the windows open or top down, even in the cool of a Florida January, because the exhaust smell in my car was suffocating, though I couldn’t smell it. The car had been checked and registered negative for abnormal fumes and leaks by Anderson Ford. She asked me never to wear any kind of after-shave lotion because it choked her. Jazz music on the car radio had to be played quietly. On-coming headlights gave her headaches. Her mother, sometimes desperate, called me for help during her daughter’s episodes of premenstrual emotionality and early menstrual discomfort. During these times, we would drive together for hours as she explained the many different colors of lower abdominal pain and how this particular kind yawned darkly before it cramped. It was more purple then any of the others. I tried to explain what I intuited but didn’t understand to her mother about the her gift of unfiltered information coming through her nerve endings, her ever readiness for surprise and her brain’s unwillingness or inability dampen or ignore what it didn’t like. She saw things in art, heard things in music that I only saw, and heard after her telling. She had tearful smiles listening to Debussy’s Afternoon of a Fawn. The flatted fifths of Charley Parker and the laconic riffs of Miles Davis made her anxious. Since then and for all these many years, the same sensually susceptible brains showed up in my life carrying a variety of woman’s names and I never lost my fascination for them. I learned that their heightened awareness extended to the spiritual realm with unusually strong metaphysical inclinations and readiness for transcendent experience. They seemed to live closer to the direct experience of God. Attending Assembly of God and other Pentecostal midweek service, I found that praying in tongues and dying in the Lord came as easily and dramatically to them as their orgasmic experiences. At the same time, distant bad news could 65 suddenly become immediate and loud in a litany of threatening thoughts that hooked and persisted through sleepless nights. They taught me to see genuinely the delicate beauty of flowers and to know in my stomach that some forms of sadness felt hollow like homesickness. In medical school I found that that many of them were the clinic patients, women and men, with unusual sensitivity to chemical odors, think Gulf War Syndrome, and fibromyalgia, which I heard as unusually sensitive awareness of normal sensory information about posture and position coming in from the bones and muscles of the body but experienced as pain. This background of odorific and somatic information is usually repressed from consciousness by the rest of us. Their medical histories contained detailed accounts about how each of their organs was feeling at the time, sensations that the textbooks say we are incapable of consciously knowing. Internists and psychiatrists often dismissed their accounts as signs of somatoform disorder, psychological conflicts expressed in the language of body feelings. In the psychophysiological laboratory, I learned these brains tended not to habituate. Each of a series of noises continued to elicit startle responses that could be picked up in brain wave recordings or in the running record of a psychophysiological, lie detector, machine. In psychoanalytic training, I learned that these brains remembered their dreams more richly than the rest of us and that treatment with over twice a week analytic sessions was potentially dangerous. The psychoanalytical situation-engendered fantasies and feelings could get too strong and exaggerated, too real. Professor Iris Bell of University of Arizona’s Alternative Medicine Research Program has, studying these brains, found slower reaction times, defects in divided attention psychological tasks, longer latencies to the first dream, and unusual patterns of odor reception called cacosmia or dysosmia. Using brain wave and cardiac interbeat interval data as markers, Bell reports the increase in the amount of alpha awake brain waves and decreases in cardiac interbeat interval variation associated with increasing sensitivity, rather than habituation, with repeated exposure to a variety of smells over time. In spite of these brains usually requiring what is known as high maintenance 66 in relationships, I continue to be erotically spellbound, in love with them in all their forms. Questions about how to think about these exquisitely sensitive women, Bell’s Syndrome exists but is rarer in men, continue to drive aspects of my scientific research. It has been variegated quest, which began with trying to find a general conceptual framework that would help my understanding of this unique capacity to be aware and process large amounts of internal and external information that escape the awareness of most of us. As one might guess, this search led to fundamental ideas about information and its inverse, the entropy indicating the amount of information transport capacity, with respect to their characterization, quantification and measurement. To get to the end from close to the beginning, we recall that it was Claude Shannon and his followers who both mathematically proved and experimentally verified that a receiver must have more entropy, less already fixed knowledge and more wondering, than the sending source, in order for the message to be sensitively and reliably received and encoded. Sensibility seems to have something to do with the readiness for information transmission afforded by the brain’s high entropy, minimal fixed information states, in its resting dynamics. Their remarkable receptivity derives from a baseline brain state like the formless emptiness of the bodhisattva’s “…no form, no sound, no feelings, no perceptions, no consciousness…” of transcendent Tibetan Buddhism as described in the Heart Sutra of The Dalai Lama. In Chinese Medicine, xu, meaning emptiness, contrasts with shi, the word for fullness, both of these complementary opposites having multiple specific meanings. Most metaphysically relevant is the characterization of xu as the emptiness of the deepest reality of being and the highest state of human spirituality. Like that aspect of Lao-Tsu’s ineffable Dao, The Way that is empty, xu indicates a mind devoid of desire, being lucid and serene. In the context of dynamical form, xu shares the structureless, non-imagery of maximal entropy systems and shi the lower dynamical entropy of fixations on form, desires and beliefs. Shigehisa Kuriyama’s The Expressiveness of the Body, elucidating historical and conceptual divergences of Greek and Chinese Medicine, notes that xu was the supreme end of self-cultivation 67 and the secret to vigor and longevity. “…to achieve fullness of life one had to abide in empty nothingness, xuwu.” In Lao-Tsu’s Tao-Te-Ching, “…the Way is gained by daily loss, loss upon loss until…by letting go, it all gets done…” William James, in The Principles of Psychology, tried to capture the subjective dynamics of the brain as an on-going preconscious stream of statistical wave processes. He envisioned autonomously increasing and decreasing coherence emerging spontaneously and from sensorial evoked thoughts via the confluence and disaggregation of statistical wave processes, “…wave crests and hollows…” that achieved temporary statistical stability by “…feelings of relation, consubstantial with our feelings or thoughts of the terms between which they (only temporarily) obtain.” In the more receptive, higher entropy brain systems, fleeting forms change without continuity, jumping from one to another with “magical rapidity,” but being not already engaged, are available for use for self-organized structure evoked by new information. Without ordered, low entropy, preconceived ideational defects in the resting random brain field, the full attentional statistical machine is available to sensitively respond in self-organized, quasi-stable states of cognitive, conative and affective integration. They then disappear; this brain relaxes quickly, ready for new experience. This contrasts with those brains that are dominated by islands of order composed of personality fixations and rigid belief systems, low entropy defects, which interfere with sensorially responsive self-organization. 68 As in most systems of authoritarian premises, precise definitions and what appears to be strict logical continuity, as in discussions of Torah among Orthodox Jews and Canon Law by Catholic bishops, classical equilibrium thermodynamic ideas that are borrowed for use out of the context of their origins, risk the calumny of their physicist practitioners. We have probably already earned more than a little distain from those quarters with our use of none-minimal or none-maximal but inbetween entropies. This phrase cannot be found in the literature of physics or, as such, in the writings of communication and information theory. In the modern theory of nonlinear motion called dynamical systems, in-between entropies can be generated by chaotic systems that are non-uniform in their rates of separation of near by points and convergence of far-away points in dynamics that have been previously described as nonuniformly hyperbolic. The energies and their transformations that fuel and support karmic escape from the personality fixations of samsara and accession to unmanifest Divine Life can occur without the loss of the richness and multiplicity of apparent reality. Big internal changes without external sign can occur in the arrangements of the ineffable and mysterious formless silence within which we have associated with states of high, but not maximal, in-between entropy. For examples, the Indian Saint, Sri Aurobindo, in the early 20 th Century, the Catholic metaphysical anthropologist, Teilhard de Chardin and currently American pandits (spiritual seekers with intellectual and academic inclinations) such as Ken Wilber, among many others over the millennia, direct us toward the goal of Nirvanically changeless emptiness without the properties of space or time. At the same time, we maintain an astute and effective yet distantiated appreciation for existential realities. The non-dual enlightenment of Integral Being or Yoga involves realizing emptiness through the world of form. There is a way of thinking about and even computing that “nothing within” and its changes. As John R. Pierce suggested in the 1981 revision of his book that made the theorems of the father of communication theory, Claude Shannon, so accessible, “…if we want to understand information-related entropies, it is perhaps best to clear our minds of any (physical) ideas associated with the entropy of physics.” 69 Nonetheless, historical comments about what the classical thermodynamic term, entropy, is and is not about are in order. We recall that Richard Feynmann, in his well-known 1962 class notes, Lectures on Physics, said that the subject of thermodynamics is the study of relationships among the heat, energetic and organizational properties of materials, without knowing their internal structure. Historically, the relational formalisms of equilibrium thermodynamics emerged before our knowledge of the internal structure of matter. For examples, the pressure in an insulated container of gas is due to molecular bombardment of the container walls, which increases with heat or compression of its volume. Compression of its volume increases its temperature and expansion of its volume leads to cooling. Note that these relationships hold without specifying the constituents and the specifics of a particular gas or solid. In his lectures, Feynman’s intuitively accessible examples of reversible thermodynamic properties are reminiscent of his on camera performance at the Senatorial hearings about the Challenger disaster. Recall that he dropped an O-ring in a glass of iced water demonstrating cold-induced rigidification of the rubber ring, which he postulated to be the cause of the fuel leak and resulting explosion. In his Lectures, he said that if one holds a rubber band between ones lips as a crude thermometer, stretching a rubber band heats up the lips and relaxing it cools them. Working the same system in reverse, and equilibrium thermodynamic systems are classically reversible, we find that heating a rubber band makes it contract. These changes involve complicated alterations in the internal arrangements of the polymeric strands of rubber, their structural properties, the details of which, for the purpose of global thermodynamic characterization, need not be known. The relationships between physical state, energy and temperature in this material were predictable from thermodynamic laws even without specific knowledge of the complex internal structure and physical dynamics of rubber. Thermodynamic theory, which makes deep conceptual connections between quantitatively measurable primitives such as heat, hotness and work and the invisible in the form of derived ideas such as energy and entropy, yielded an 70 enormously rich and logically consistent intellectual framework from within which to characterize macroscopic behavior composed of unknown molecular mechanisms. Ideas about entropy grew out of William Thomson's (a.k.a Lord Kelvin) thermodynamic laws about energy conservation and its allowable transformations. Later Clausius decomposed the energy into that which was available for mechanical work, called work-content, and that which was not, called transformation content. He referred to the transformation content, a reflection of what changes in the internal order properties of the system that occurred as a concomitant of changes in energy and heat, as the entropy. Rudolph Clausius added the word entropy as a thermodynamic property to the conceptual armamentarium of theoretical physics in about 1865. This followed the earlier work of the French engineer, Nicolas Leonard Sadi Carnot, who was trying to develop a theoretical framework within which efficiencies in heatgenerating engines might be understood. It implicated positive, > 0, changes, d, in entropy, S, with changes in time, t, i.e. dS dt > 0, entropy is increasing in time, as a concomitant of the inevitable mechanical inefficiencies in an energy driven system. The resulting losses in the form of wasted energy show up as increases in molecular motion, which could be estimated from the increases in heat. Wasted energy dissipated as heat increases the amount of random motion and volume occupied by the surrounding molecules in physical processes involving heat, pressure, vaporization, condensation and work; all elements of that era’s dominant physical metaphor, the steam engine. The highly developed, multifaceted, often quite abstract formal characteristics of the inferred property, entropy, prevent glib definitions and generalizations. In the context of Kelvin-Clausius theory, the entropy of a closed system will remain the same if it is isolated from any matter or energy exchanges with the environment. If heating a system such that the change, d, in heat, Q, is positive, i.e. dQ > 0, it experiences a rearrangement in its microstructural motions, but the temperature is left unchanged. The (inferred) entropy, S, increases (i.e., dS > 0) as the ratio of change in added heat, dQ, over the unchanging, absolute 71 temperature, T. Thus, one definition of entropy change is dS = dQ/T. In classical contexts, dS is expressed in units of heat called Joules per degree of absolute temperature in units Kelvin, the temperature in Centigrade plus 273.16 o . The bestknown physical image involves the heat-energy transfer to and from heat baths called reservoirs as intermediate actions of the work of the heat driven engine executing what has come to be known as the Carnot Cycle. The same formulation emerges in this more concrete context: the heat, Q, transfer, dQ, at a particular absolute temperature, T, dQ/T, has been used to define an entropy change, dS = dQ/T related to some not-need-to-know-about specific alteration(s) in a system’s internal physical properties. If one allows some loose thinking about heat-induced increases in the statistical randomness of molecular motion in the above reservoir that is associated with the loss of useable energy, the positive entropy change, dS > 0, is vaguely relatable to the kinds of information entropies to be discussed below. If a gas trapped in an insulated, physically isolated, closed cylinder is allowed to expand infinitely slowly, reversibly, called adiabatically, pushing up the piston that closed off its end, the gas will become cooler, energy having been expended doing the work of lifting the piston. Defined as an isolated system (of course no where in the real, nonlaboratory, world can this condition of absent exchanges of energy or matter with the environment be found), it is a reversible process, because returning the energy of the work by, again, infinitely slowly pushing down on the piston and compressing the gas to its original volume, returns it to its former temperature-defined energy state. In this historically prominent thought-toy of physics, there has been a reversible change in energy but no changes in the entropy, dS = 0. The gas’s heat, temperature (and energy and volume) can be completely restored in this metaphysically mythic classical thermodynmical tale of an entropy-conserving, reversible process. While fixed entropy and independence of the specific path is the case for the above noted abstract reversible cycle, in the real, irreversible orbits of most physical and all biological systems, entropy increases, dS > 0. Walter Nernst’s 1907 heat theorem yields a zero point from which to determine a difference measure in the 72 postulated, real physical world of ever-increasing entropy. He showed that at an absolute temperature of zero, entropy is zero. We can illustrate an approach to this singular state by placing a heated metal rod in ice water which would result in a decrease in the entropy of the rod’s molecular motions by dQ/ T 1 < 0, the cooling reducing the complexity of molecular motion in the metal bar and an increase in the entropy of the water by dQ/T 2 > 0 indicating an increase in the amount and complexity of the surrounding water’s molecular motions. Of course the heat moves from metal rod to the water as T 1 →T 2 making dQ > 0 positive and the entropy change, dS = dQ/ T 2 - dQ/ T 1 , also positive. In another simple example, producing friction by rubbing a surface generates heat, dQ > 0, at a temperature T. This induces a positive change in entropy, dQ/ T > 0, in the form of increasing amount and complexity of the patterns of molecular motion in the air surrounding the rubbed surface. Using another related and well-known thermodynamic thought toy, the original isolated, insulated body of gas in the cylinder is partitioned by a membrane into two chambers, one containing all the gas with its temperature, pressure and ability to do mechanical work and the other a vacuum without these properties. This equilibrium state is changed into another equilibrium state by suddenly removing the membrane, filling both chambers with gas and, while increasing its entropy irreversibly, dS > 0, removes at least some of the gas’s ability to do piston raising work. In the context of classical thermodynamics, it is in this way that irreversibility can be defined by its associated increase in entropy. Though there has been no change in total energy in this insulated closed system, an increase in entropy means a decrease of the energy available for work. The increased disorder in the gas is associated with the loss of ability to convert heat, thermal energy, into mechanical energy. Historically important and still available elementary texts by Enrico Fermi (1936), Mark Zemansky (1957) and Herbert Callen (1985), among many others, explicate clearly the formal, but far from biologically relevant, classical theory of the physical entropy of closed equilibrium thermodynamic systems. Growing in part out of the formal thermodynamics of physics, statistical mechanics offers yet another set of intuitions about the not-necessarily-known 73 molecular details associated with changes in entropy. These ideas are closer to applicability in problems of making measures on the behavior of biological systems. Very generally, in the statistical mechanical context, an increase in entropy means a decrease in the order, which can be a quantitative observable reflecting a decrease in predictability and/or knowledge about the system. For example, we can locate the molecules of the gas more accurately when they are all on one side of the membrane-partitioned cylinder compared with the situation when the membrane is suddenly removed. This accompanying increase in ambiguity and decrease in knowledge in locating a set of gas particles reflects a statistical mechanical view of increases in entropy. Can anything general be said about the bounds on an increase in entropy? The statistical developments of the Yale mathematical physicist, Josiah Willard Gibbs (about 1875), consonant with the logical arguments of the Greek mathematician, Constantin Caratheodory (about 1910), conclude that the entropy increase goes to the maximum allowed by the constraints imposed by or upon the system. A change in likelihood as a probability is a characteristic way to quantify the entropy change, reflecting an alteration in knowledge or its reciprocal complement, uncertainty. The system’s entropic uncertainty said more colloquially, and relevant to the Bell Syndrome’s women of my life, is its capacity for surprise. A statistical mechanical approach to the total entropy of a bounded set of molecules in motion involves summing this property across all the participating molecules. We let N be the number of particles involved. As a problem in Newtonian mechanics, each of the N particles is represented in 6N dimensional phase space. That means that each point represents one of the N molecules in the three dimensions of location space plus three dimensions of motion space as its velocity, more specifically, the product of mass times velocity called momentum. This adds up to 6 dimensions of measurement. This so called phase space reconstruction of the molecules of a gas as individual particles are a daunting task, though fast computers and new algorithms are making computations from first principles more generally attainable. Those based on the first principles of short-range repulsion and long-range weak attraction among particles and the bumper-car collision 74 dynamics between them can now be implemented if the system of particles being simulated is sufficiently small and the computer simulation is for very short times. To transform the entropy into something more statistical and global, we return to the theoretical work of Ludwig Boltzmann whose formalism was used previously to quantitate pathological developmental simplification. He assumed that given a set of constraints, say the closed volume, V, of a box, B, of a fixed size, V (B), the orbit of each particle would eventually explore all the space in the box that was available to it. Boltzmann’s entropy became a constraint dependent, n- dimensional volume measure, with the assumption that the entropy, S, equals the logarithm of this volume measure, S = ln V (B). To calculate a value for the entropy, compute the volume of the molecular motion as determined by the invariant constraints of the system, such as the volume, temperature, pressure and/or its total number of molecules. We may partition, discretize, the volume up to some limit of resolution such that it is divided into Ω small boxes, each containing the representation of a particular state. Making the same assumptions of closed system, equilibrium thermodynamics, such a system is completely isolated from outside sources of matter and energy, it spends equal time in each of its Ω available states. In such a case, the characteristic occupancy time of any state is inverse to the number of states available, e.g. 1/Ω, and the system’s entropy is maximal for that set of states. Under these conditions, S = k ln(Ω), where the k term is the Boltzmann constant that contributes to the numeric units of entropy, as above, in Joules of heat /degrees Kelvin of the temperature. If the system is in contact with a heat bath, but cannot exchange matter with its environment, it is called diathermally isolated. The distribution of times spent in the available states of a classical diathermally isolated system of gas molecules can be represented by what is called a Boltzmann distribution of probabilities of state occupancies, ρ (as a function of their energy level, more measurably, their responsiveness, susceptibility, to heat). Here the characteristic time of the system spent in each state varies as the particular state’s probability. 75 Leaving the framework of physical thermodynamic entropies entirely, the entropy of information was introduced in the context of communication engineering in electrical and electronic devices. The metaphorical machine for the current age of entropy, analogous to the role of heat and steam engines in classical thermodynamics, is the computer. Energy in this context is a relatively trivial property. Ammeters and other monitors of load are unable to discriminate between a computer actively engaged in encoding and computation or one simply maintaining its dynamic memory while resting in computational readiness. This situation is very analogous to the results of early work discussed previously on the metabolic rates and sources of the whole brain’s energy, oxygen and glucose metabolism, by National Institutes of Mental Heath’s Seymore Kety and Louis Sokoloff and the State of Illinois Thudicum Laboratory’s Harold Himwich. Using whole head arterial-venous, energy-in, energy-out, differences, they could not demonstrate differences in rates of whole brain metabolism between states in which the human subjects were engaged in solving mathematical problems or deeply sleep. In today’s brain imaging research, using a variety of physical reflections of the brain’s metabolic activity, it is the differences in regional distributions of metabolic activity that are relatable to subjective and behavioral states, not differences in total amount of energy expended. In graphically coded representations of the regional metabolism of the brain in action, one or another or many areas “light up” and others “grow dark” in correlation with changes in thinking, feeling and action. The entropy first developed by Claude Shannon was formalized for use in 1948 in what was then called communication theory and now information theory. It represented a measure of the ambiguity and uncertainty that had the potential for being resolved by new knowledge. In this context, entropy and information were obviously complementary descriptors. A message that informs us about which of ten possibilities should be chosen contains less information than one that informs us about the proper choice to be made from among a thousand possibilities. The entropy of communication theory is a measure that is computed on uncertainty. The information reception capacity of a system is dependent upon the amount of 76 uncertainty in the receiver that pre-existed the receipt of the message. In the binary coding scheme of digital electronic operations, the unit of information is the bit, a choice made between 0 or 1 in the resolution of a two state ambiguity at each place of some power of two number of places. Our relatively common computers these days have 32 or 64 bit processors. If these 0,1 choices are made in a random sequence in which each step is independent of the previous one, the sequential probabilities, � �� � are multiplicative: e.g. the probability of getting two 1’s (heads in a fair coin) in a row are the product of each 0.5 probability: ρ 1 = 0.5 × ρ 2 =�0.5 = ρ 1 ρ 2 = 0.25. Using the common base ten system of logarithms to demonstrate the algebraic fact that multiplicative probabilities are logarithmically additive (and ignoring the minus sign that comes with making logarithms of the decimal fractions of probability), we notice that log 10 (0.5) = 0.693147 and log 10 (0.25) = 1.386294 and that 0.693147 + 0.693147 = 1.386294. The dot-dash choices of Morse code machines, the go, no-go gates of transistors, the open versus closed ion channel-mediated neuronal membrane discharge and the left, right spins of the single electrons of today’s quantum computers lead naturally to an information encoding of multiplicative sequences as the sum of logarithms in base (equal to the number of available states) two, each ρ�= 0.5 choice called, log 2 (0.5) = 1, a bit. Shannon’s 1938 master’s thesis mapped George Boole’s algebraic scheme for doing yes-no, either-or computation onto current switching devices such that circuit closed was “true” and circuit open was “false.” Using Boole’s laws such as “Not(A and B)” always equals “(Not A) or (Not B)” led to schemes for circuit routing through electronic gates which also serve for information storage in gadgets ranging from cell phone directories to computer hard disks. Following Claude Shannon, each logarithmically additive entropy term is expressed as the sums, Σ ι � of its probability, ρ ι , times the probability’s logarithm, Σ ι (ρ ι �× log 2 ) (ρ ι ��in base two. A logarithm is an exponent of its relevant base such that, for example, the logarithm, base two, of 2 × 2 × 2, 2 3 , = 3 and 3 bits can encode eight binary (0,1) numbers: (000, 001, 010,011,100,101,110, and 111). Shannon used a hill-like, called convex, entropy function S (ρ)= -Σ(ρ ln (ρ)). The amount of 77 information required to gain knowledge of an event is dependent upon the probability of its occurrence. log 2 (0.5) = 1 is the maximal entropy when modeling the equilibrium entropy of an independent random 0,1, (heads or tails) series of informational states as might result from flipping a fair coin a large number of times. This value would be maximal when the coin was fair, ρ(heads, tails) = 0.5, and the entropy would be 2(number of allowed states)×0.5(probability of occupying each state)×log 10 (0.5) = 0.693147...or in bits, log 2 (0.5) = 1. More generally, if system’s behavior is distributed equally among its possible states, the Shannon entropy is maximal and equal to the logarithm of the number of defined states, for example, log 2 (2) = 1. Shannon’s classical equation about information content says the amount of information, I = -ρ log 2 ρ, measured in bits. The minus sign in this reciprocal relation indicates that the information content of data, I, goes up as the probability of occurrence of the observed data, ρ, goes down. Since soon we will be talking about brains and their various styles of information encoded content as well as its transmission, we note the other famous Shannon theorem dealing with limits on the channel capacity, C, for information transport is C = Wlog 2 (1+S/N) where W is bandwidth, the range of frequencies available for information transport, S is the strength of the signal and N is the strength of the noise. Recall that the log 2 (1) = 0 so only the signal-to-noise ratio, S/N contributes to the value of the product of the multiplication by bandwidth, W. Transparent clinical examples come from studies of the perceptual and cognitive decline in normal geriatric patients in which the range of aural frequencies (W) heard without augmentation decreases with age as does the frequency range (W) observed in their resting brain waves. The inattentiveness of the obsessively worried ruminator can be used as an example of brain channel capacity being reduced by the amount of on going head noise, an increase N, which, of course, reduces the value of S/N and therefore C. Measures of the informational complexity of systems in motion, in contrast with the information content of a static equilibrium state, are of dynamical entropy. Dynamical entropy is often called H, in contrast with thermodynamic and/or informational entropy, S. One can begin with a representational image of the 78 location, velocity and directional tendency of every point generated by a dynamical system by an arrow on the surface of action, the manifold, of a dynamical system. This field of arrows indicating directional and strength of motional tendencies is called a vector field. A vector represents its location at the base of the arrow, its velocity by the length of the arrow (called the modulus) and the direction of the motion by the direction of the arrow. If we regard all moduli as equal to one, every vector on the surface has the same length. The resulting graphs are called direction fields. Looking at a stop-action photograph of any point on this surface, its associated vector informs about where the system would take it over the next unit of time. The whole surface can be marked by initial points, which the dynamical systems move as they generate patterns of orbits of moving arrows in time. The following two brain and behavioral experimental circumstances make this depiction and its relevance to dynamical entropy more concrete. We review in more detail the concrete and visualizable findings from experiments requiring the quantification of characteristic patterns of motion in animals and man. They can be embedded into a similar surface-like setting, which might be called a behavioral manifold. For examples, my students from the past, Martin Paulus and Mark Geyer, now Professors at the Medical School of the La Jolla branch of the University of California studied the effects of psychotropic drugs on the patterns made on the floor by rats of various genetic strains while they wandered about, in exploratory behavior in a bounded space. Monitored by a video camera placed above the ceiling less cages, the patterns made by the paths taken by the rats over time were reconstructed as vectorial orbits on a behavioral manifold. This manifold was then repeatedly partitioned, covered with, from just a few large, in graded progression, to many smaller boxes, each partition composed of rectangular lattices of a particular size. Units of time were also partitioned into range of units from larger to smaller durations of observation. Differences in the rat’s genetic strain as well as injections of stimulants, antidepressants or antipsychotic drugs resulted in characteristic and discriminable path geometries mapped onto the behavioral manifold as orbital patterns. Each path was encoded as a sequence of size-dependent numbered boxes that were entered and occupied 79 or left. The new information being generated by the pattern of spatial orbits took the form of sequences of numbers or symbols representing the sequence of labeled boxes. The complexity of these numeric or symbol sequences was then quantified in a variety of ways including the use of two fundamental measures of dynamical entropy. One measure reflects how many new, previously unexplored boxes were entered by the rat per unit of time. This rate represents a percent of the possible. The second measure reflects how much of the time did the rat in each box visited as a distribution of the probable. The rate of expansion of the possible and the relative time in occupancy of these possibles, the probables, form the bases for the computation of these two kinds of entropies. For example, the work of Paulus and Geyer showed that the administration of a very small amount of stimulant drug, compared with a salt water control, led to an increase in the first measure of the number of new, previously unexplored, boxes entered per unit time. With respect to the second measure, the stimulant drug augmented exploratory activity was also more uniformly distributed over the possible boxes, making for more uniform probability. Administration of higher doses of stimulant drugs, at a critical dose, led suddenly to more spatially and temporally restricted and stereotyped patterns of motion of the rats, compulsive circling alternating with frozen sniffing. Both contributed to a decrease in the possible and nonuniformity in the distribution of the probabilities. In man, low doses of amphetamine tend to increase the rate and creativity of thought streams and high doses generate fixed ideas and paranoid delusions. In the statistical approach to nonlinear dynamical systems, timedependent generation of new possibilities is called topological entropy, H T and the entropy associated with the distribution of probabilities is called the metric entropy, H M. These kinds of entropies have also been used to quantitate characteristic patterns of in human behavior as well. We have previously mentioned these measures as used in human experiments by Karen Selz, a Research Professor of Psychiatry at Emory University in Atlanta. Recall that she devised a set of experiments leading to unobtrusive measures made on human subjects by asking them to remove, as many as they 80 could, the dots in a lattice, one by one, from the computer screen, by clicking on each point with a mouse. In some experiments, after removal, the dot reappeared in fifty milliseconds, in the “fast return condition”, or after one-second delay in the “slow return condition.” Unbeknown to the subject, the path made by the motions of their mouse on the computer screen over time while removing dots were reconstructed as a path on a fine to coarse grained box-partitioned behavioral manifold. Entropic indices of the rate of expansion of the possible, number of new boxes entered, reflecting H T , and the relative occupancy of the partition of the possible, reflecting H M , the distribution of probabilities with respect to the boxes, could then be computed. For examples, Selz found that the spatial and temporal patterns of computer mouse motions made in this dot search and destroy task correlated highly with the subjects’ age, sex and personality types as defined by profiles from the Minnesota Multiphasic Personality Inventory, MMPI, and the Structured Clinical Interview, SCI, associated with the standard Diagnostic and Statistical Manual, DSM IV. She found that subjects whose personalities were like my high self-sensibility girlfriends demonstrated high indices of both H T and H M . The actions of nonintegrable nonlinear differential equations, not solvable by the usual techniques of integration, can be transformed into graphical images by plotting their orbits in abstract phase spaces with the three physically measurable coordinates of location x (or some other temporarily fixed value), velocity y (the rate of change in the location or measured value) and z acceleration (the rate of change of the rate of change in location or value) in x, y, z space. Graphical representations of the system in action in phase space can serve in place of analytic solutions to the equations. This idea was one of Henri Poincare’s major contributions to mathematics and physics, and has come to be the centerpiece of the qualitative theory of differential equations. The often point-to-point unpredictable but globally and qualitatively characteristic geometric shapes of the orbital patterns in abstract phase space are the objects of interest. There are visualizable representations such as cycles as circles and statistical measures made on these objects such as the H T and H M entropies and the in-betweenness (neither maximal nor minimal) of their difference. 81 A global statistical context for these qualitative differential systems was inspired by the Russian mathematician, Andrei Nikolaevic Kolmogorov. In his now famous foundational talk about the stability of classical mechanical systems in the final session of the 1954 International Congress of Mathematics, he gave public birth to, among other ideas, what has come to be called the ergodic or statistical, measure theory of dynamical systems. Here, ergodic means the existence of an invariant statistical measure on the phase space attractor of the system that can be obtained using a variety of equivalent methods and beginning the count at any of its points. Two phase space objects generated by a dynamical system may look different in phase space but their statistical measures may all be the same, i.e. invariant. These qualitative orbits in a box-partitioned space can be visualized as Paulus and Geyer’s rats exploring a space and Selz’s path sequences of computer screen dot quenches produced by clicking on them with a computer mouse. A precursor of Kolmogorov’s ergodicity was the earlier ergodicity of Ludwig Boltzmann. This describes a suitably partitioned system such that equivalent values come from quantitating the behavior of one single orbit exploring the space of the lattice of boxes over very long times time as those obtained from a single aggregate photograph of all orbits run from all possible starting places simultaneously. The ergodicity of gas-like molecular randomness implicates systems being in one of only two possible equilibrium statistical states: measure zero (at most occupying a single point, zero, minimal entropy) or its “complement,” full measure one (occupying all available space in a state of maximal entropy). Joseph Goldstein, a well known teacher of meditation, giving advice recorded in Daniel Goleman’s 1977 book on the subject said that all methods of nirvana directed meditation amounted to “…simple mathematics …all systems aiming for One or Zero—union with God or emptiness.” In place of the maximal or minimal values for the H T and H M entropies of these states of transcendence, we in the world of samsara are stuck in states of inbetween entropy which invariant statistical measures of on phase space shapes help quantify. To generalize measures made on rat and computer mouse paths to more general and idealized systems, after plotting an orbital path in a phase space, we 82 may partition the space of values taken by the journey of the orbital action generated by the equation over time with rectangular grids of increasing fineness. The result is an equipartition of phase space such that there is at most one orbital point in each rectangle of the grid, with, of course, many rectangles in the finer grids being empty. This final grid partition is called a generating partition. The proportion of the available boxes of the partition occupied by points is called its area or volume measure. This measure has been given a variety of names including Liouville, Haar and Lesbegue measures. If every box is occupied, it has measure one. If at most one box, it has measure zero. If we allow partitions to be non-uniform and/or not fine enough to be generating and apply probability weightings for how many points fall into each particular box of the grid, the method is called the Sinai-Ruelle-Bowen or SRB measure after Kolmogorov’s students and followers, the Russian, Ya Sinai, the Belgian Frenchmen, David Ruelle and the American, Rufus Bowen. Similar to the SRB measure, the distribution of box occupancy probabilities multiplied by their logarithms and summed over all cells of the partition yields a statistical measure that is close to the informational entropy of Claude Shannon as described above. It is called the metric entropy ( H M = -Σ(ρ i ln(ρ i )), where H means entropy and ρ i is the proportion of the total observations that occupy cell i of the phase space or state space partition. It was the above noted Russian father of modern dynamical systems, Kolmogorov, who in 1956 proved that the Shannon metric entropy is a quantifiable invariant of systems even in very complicated motion. Stanford University's Donald Ornstein won a Field’s Medal (the under forty year old mathematician’s Nobel Prize) for his late 1960’s work proving that the Shannon metric entropy, H M , was the only invariant for a large class of appropriately defined, expansive (near by points separating in time) dynamical systems. Recall that we refer to metric entropy reflecting the relative occupancy as probability among the possible boxes (or states) as H M . H M is maximal when the percentage occupancy of all occupied boxes is uniform. IBM’s Roy Adler in New York and Brian Marcus in California, Hebrew University’s Benjamin Weiss, Warwick University’s English mathematicians, William Parry, Peter Walters, Mark Pollicott and others developed and proved the relevance 83 of a related measure of the rapidity of dynamical expansion, the generation of new information seen as the rate of entering new boxes of the partition, a logarithmic rate of expansion of the possible. Counting the number of previously unoccupied squares entered by the dynamical systems orbit per unit time over the generating partition, for instance, yields an estimate of entropy that, as in the rat and computer mouse examples above, is called the topological entropy, H T . H T , is about how much new information is being generated by the system per unit time. Theorems have been proven that H T is a maximal estimate of the global dynamical entropy with H M proven to be a minimum estimate. Monitoring single or aggregate molecular motion in a system with the maximum randomness of a space filling gas, we find that, on the average, every box is entered and occupied uniformly such that H T = H M or said another way, H T – H M = 0. As evidenced by the above described experiments in rats and people, the same entropic relations (but usually not with maximal or minimal measure) can be found in biological systems. We have previously described the manifold geometry of a generic (typical, idealized) nonlinear dynamical systems as hyperbolic defined by the presence of simultaneous but decomposable components of the motion including the straight ahead and round and round actions on the center manifold, the new possibility generating, expansive, away from the center manifold motions along unstable manifolds and the back to the center manifold, contracting motions, along the stable manifolds. Uniform expansive and contractive influences in the flow leads to mixing of the order of the initial sequence of the values inscribed by the orbits. This results in maximization of the entropies and satisfaction of a concomitant of the uniformly hyperbolic condition, H T – H M = 0. These clean and mathematically proven findings do not hold for the quasimess that is human neuropsychobiology. Enmeshed as most of us are in only intermittently random or nonuniformly hyperbolic systems with the in-between entropies of the only apparently real world of maya, H T – H M ≠ 0. How the H T – H M = 0 of uniform hyperbolicity fails, H T – H M ≠ 0, and along with it the dispassionate detachment of entropic emptiness and fullness, becomes a problem not unrelated to the existence and quantitative qualities of personality styles and their dissolution 84 with return toward but not reaching the maximally entropic openness, flexibility and naïve credulousness of the in Jesus and Holy Ghost occupying transcendent dynamical states. We are all stuck somewhere in the range of measures indicating in-between entropies. Further Readings for Sensual In-Between Entropies Ecstasy in Secular and Religious Experience, Marghanita Laski, Tarcher, Los Angeles, 1961. The Role of Neural Plasticity in Chemical Intolerance, Barbara A. Sorg and Iris R. Bell, Ann. N.Y. Acad. Sci. Vol. 933, 2001 The neuropsychiatric and somatic characteristics of young adults with and without self-reported chemical odor intolerance and chemical sensitivity, I.D. Bell, C.S. Miller, G.E. Schwartz, Arch. Environ. Health 51:9-21, 1996. Application of entropy measures derived from the ergodic theory of dynamical systems to rat locomotor behavior, M. Paulus, M. Geyer, L. Gold, A. Mandell, Proc. Natl. Acad. Sci. (USA) 87:723-727, 1990. Long-range interactions in sequences of human behavior, Martin Paulus, Phys. Rev. E. 55:3249-3256,1997. Mixing properties in human behavioral style and time dependencies in behavior identification: The modeling and application of a universal dynamical law. Karen A. Selz, UMI, Ann Arbor, 1992. A family of autocorrelation graph equivalence classes on symbolic dynamics as models of individual differences in human behavioral style, Karen A. Selz and 85 Arnold J. Mandell, In (ed. R.R. Vallacher and A.J. Nowak), Dynamical Systems in Social Psychology, Academic Press, San Diego, 1994. Toward a neuropsychopharmacologicy of habituation: a vertical integration. Arnold J. Mandell, Math. Modeling 7:809-888,1986. Thermodynamics, Enrico Fermi, Dover, N.Y. 1956. Thermodynamics and Statistical Mechanics, Peter T. Landsberg, Dover, N.Y. 1978. Ergodic Theory, Symbolic Dynamics and Hyperbolic Spaces, T. Bedford, M. Keane and C. Series, Oxford, Oxford, 1991. The Mathematical Theory of Communication, Claude E. Shannon and Warren Weaver, U. of Illinois Press, Urbana, 1963. Science and Information Theory, Leon Brillouin, Academic Press, N.Y. 1962. Brain Metabolism and Cerebral Disorders, Harold E. Himwich, Williams and Wilkins, Baltimore, 1951. 86 CHAPTER 5: SOME ENTHEOGENIC ENTROPIES In the spring of 1968, members of my laboratory team were looking for new brain metabolic pathways of the essential amino acid tryptophan, the dietary precursor of the human mood, sleep and libidinal neurotransmitter, serotonin. After struggling for several months to identify an apparently new compound, which turned out not to be new but only new in the brain, we collected evidence for a human brain enzyme that could catalyze the production of an LSD-like hallucinogen, dimethyltryptamine, DMT. Tracing its metabolic origins, we found that DMT was derived from tryptamine, a common metabolite of the essential and omnipresent amino acid, tryptophan. This enzyme and its metabolic product were located in highest concentrations in brain stem systems that influence the neural regulation of the heart, blood pressure, temperature, breathing, vomiting and primitive approachavoidance behavior. It was also found in limbic brain nuclei thought to modulate the emotional coloring of perception and thought. Richard Wyatt, working at the National Institutes of Mental Health found DMT in the urine of schizophrenic humans. He also showed that DMT increased significantly if tryptamine’s normal pathway for degradation was blocked by monoamine oxidase inhibitors, such as 87 Nardil, Marplan, Eutony, Parnate and others of a then common family of antidepressant drugs. The presence of a DMT-generating enzyme in human brain was particularly exciting because we knew from the work of Harvard botanist, Richard Shultes and others, that DMT and the monoamine oxidase inhibitor, beta carboline, are combined in a mixture of the leaves of a shrub and the bark of a vine, both Amazonian plants, used together by the shaman of Peru, Colombia and Ecuador for thousands of years to evoke mystical experiences in themselves. In their state of chemically-facilitated, spiritual transformation, they were better able to engage in healing and divination of others. More recently this and other similarly acting biochemicals have been called entheogenic, “connecting to the sacred within.” Consistent with our neurochemical findings in human brain, the shamanic concoction, called by many names including ayahuasca and yage, combined the DMT containing plant, Psychotria viridis, with an extract of a vine with the powerful monoamine oxidase inhibitor properties of the beta carbolines found in Banisteriospsis caapi. In 1975, working with a graduate student, Louise Hsu, we found that the mammalian brain could also synthesize beta carbolines. This family of compounds from the vine protects the tryptamine substrate as well as DMT from metabolic degradation such that it could circulate in the blood long enough after oral ingestion for enough to cross the blood brain barrier to induced prolonged and dramatic alterations in perceptions, feelings and thoughts. In addition, the carbolines of the Benisteriospsis component extended the time of action of DMT beyond the 15-30 minutes of effect of DMT when injected alone in human subjects. We found it fascinating that the human brain made combinations of DMT and beta carbolines similar to the blend that indigenous shamamic chemists discovered as an entheogenic from plant sources. Ralph Metzner, in the introduction to his 1999 collection of papers called Ayahuasca concluded that “…it is widely recognized by anthropologists as being…the most powerful and most widespread of the shamanic hallucinogens.” William Burrough in a 1953 City Lights published book written with Allen Ginsberg, The Yage Letters, said that yage “…gave entrance to a city where all human 88 potential is spread out in a silent market…” It was generally believed that with adequate spiritual preparation, ayahuasca could generate transcendent states that allowed access to ones inner being and the beings of other worlds that could serve as sources of mystical knowledge and healing. The Shams dervish of the 13 th Century, wandering the Turkish portion of the Silk Road, used the word sohbet to describe the inner land of mystical conversations about mystical subjects that their turning meditation, whirling, and the shaman’s entheogenic compounds such as DMT give entrance. The question was whether our finding of DMT and its human brain enzyme had been an artifact, an accidental laboratory fluke. Members of my neurochemical research teams at the University of California Medical Schools in Irvine and La Jolla, notably Dr. Lee Poth, now a professor of pediatric endocrinology at the Uniform Services Medical School in Washington D.C., demonstrated that the DMT synthesizing enzyme existed in the brains of recent accident victims that as far as we were able to learn from their family and social histories, had been completely psychologically normal. More than a little bit startled by this finding and worried about making a sensational scientific mistake, we repeated the experiments with a variety of controls with the same findings. Though our original estimates of the human brain enzyme concentration were on the high side, we confirmed the general finding and published them in Science in 1969 and Nature in 1970. Our carboline work was published in the Journal of Neurochemistry in 1975. A year or so after our Nature paper was published, the Nobel Prize winning neuropharmacologist at the National Institutes of Mental Health, Julius Axelrod, confirmed the presence of the DMT biosynthetic enzyme that converted the tryptophan product, tryptamine, to DMT in mammalian brain tissue. We were both delighted and relieved. We speculate, perhaps too grandly, that this finding, along with the beta carboline human brain synthesizing capacity, supplies one of many possible neurobiological and neurochemical mechanisms for the claims of the cross-cultural universality of mystical experience. We all had human brains with these enzymes. The idea that the phenomena accompanying primary religious experience were common to all cultures was a major theme of the life’s work of the philosopher- 89 psychologist, William James, and was studied using fieldwork by anthropologists such as Bronislaw Malinolowki as described in his classic book, Magic, Science and Religion. Was this neurochemical-behavioral organization an evolutionarily adaptive mechanism selected so that some spiritually gifted individuals self-selected from a severely stressed population could escape and then lead the rest of us out of a sense world that had become intolerable? Could this be an antidote for the hopeless, without materialistic solutions and trapped in a belief system of spiritual nihilism? Was this a brain chemical transcendence escape and spiritual delivery system for the suprapsychological survival of those in dire need? As the 13 th Century Islamic mystic, Jelaluddin Rumi, has written, “If a tree could fly off, it wouldn’t suffer the saw…” and more concretely, “…if you can’t go somewhere, move into the passageways of the self…,” a spiritual escape via a neurobiological road to the God-space within. What followed were a few years of occasional exploration of an “inside out” understanding of the mystical states evoked by the entheogenic family of chemicals. There were varieties of settings for these personal experiments. I found myself LSD-lost, circling endlessly in the tall silence of a Northern California redwood forest. I tried on Hunter Thompson’s mescaline lenses for the experience of Las Vegas unfiltered. I was expertly mentored in these quests by a distinguished collection of guides: Cultural anthropologist Michael Harner who taught me about the yage and datura use among the shaman of the Jivaro; Social anthropologist, Barbara Meyerhoff introduced me to the personal renewal rituals of the peyote cactus-using Huichol Indians of the Southwestern Sonora Desert; Neurochemically sophisticated Sidney Cohen, founding director of the National Institutes of Health’s Institute on Drug Abuse, told me stories of his involvement with Aldous Huxley and Barbara Brown in the Los Angeles covey of early American LSD explorers; organic chemist Albert Hoffman, Sandoz’s designer of a series of ergot alkaloids including LSD, told me stories of his accidental post-sniff hallucinations while returning home on a bicycle; An anonymous group of us conducted personal experiments with Sacha Shulgin, the University of California at Berkeley professor who first synthesized and tested the mescaline-derived, Ecstasy series of compounds; We 90 did some work with the dissociated anesthesias (producing wide awake but not there states) having consulted with John Lilly, a brain scientist who used these agents as a courageous self-medicating explorer of sensory isolation tanks; I met several native shamanic practitioners including the Huichol Indian that was the model for Don Juan in Carlos Castanada’s five volumes of pseudoethnography written up in my essay “Is Don Juan Alive and Well?” in The Pushcart Prize of 1977. Issues of culture and brain chemistry came together in several accounts about entheogenic, mescaline-containing peyote use among the Huichol Indians in a book edited by Kathleen Berrin and Thomas Seligman of the San Francisco Art Museum called Art of the Huichol Indians. Over these years I collected many nauseating, upper and lower bowel wrenching and ecstatically transcendent and exhausting day-long episodes of the angular geometries of visual pattern-generating DMT, the animistic breathing of bush and flower breathing peyote cactus, the darkly forbidding shadows of the psylocybin-containing mushrooms, the irreversible rocket launches into the electrically buzzing, kaleidoscopic circus of LSD-containing vials from Sandoz and the optimistic, trust engendering, expansively warm rush of six of Sacha Shulgin’s gregarious, rave dancing, chlorinated, methoxylated and ethoxylated phenylethylamines which he had, years before, synthesized for “an undisclosed purpose” for the Dow Chemical Corporation under contract with the U.S. Army Chemical Corps. The best known of the latter group remains part of the rave culture as Ecstasy. These agent’s peaks are flooded with exaggerated, caricaturizing images of people’s faces and a belief in the mindedness of animals and even the embodiment of inanimate things. Evoked are simultaneous and diametrically conflicting interpretations of the same social context, heteromodal sensory fusion called synesthesia so that sound bespoke color and smells induced music, habitual thoughts rearranged as new ideas in what is experienced as exciting new insights, and, most of all, that which Louis Lewin, Berlin’s early 20 th Century Freud of psychotropic drugs in his book Fantastica, called gladness of the soul. Timothy Leary wrote of entheogenic escape from the habitual human brain’s mental- 91 manipulative and socio-sexual circuits gaining access to the rapture and ecstasy brain pathways on the way to the new planet within. What is seldom written about is the aftermath of chemical entheogenic agents. After the several hours of fireworks, all of these entheogenic agents, some more than others, gifted me with weeks to months of more self-sufficient, emotional fullness and ease in the conduct of living that was less contaminated by narcissistic preoccupation or defensive distantiation. I was left with increased interpersonal sensitivity and a noticeable repair of my deficiencies in aesthetic sensibility, particularly for the visual arts and landscapes. What were once two dimensional, trivial, beside-the-point, scattered copses of trees and apparently casual arrays of plant life in the Boboli Gardens behind the Palazzo Pitti in Florence, became the grandly structured, botanical wonder of increased dimension, communicating awe filled new perceptions of its previously unseen beauty. For the first time, I found myself walking slowly and stopping for several minutes, wordless, spellbound, in front of the modern art pieces of New York’s Guggenheim Museum. Lost in the experience, I found myself exclaiming to no one in particular, “I can see!” The delicacy and deliciousness of post-entheogenic agent’s new and beautiful everything made me tiptoe watchfully so as not to injure an ant. Feelings of omnipersonal kindness and generous compassion were without prideful selfreflection. This state of grace felt like an invasion of a shimmering presence that made contact with my other, generally unknown to me, life. It brought new perceptions, feelings and ideas for which I was moved to give thanks. I began to think I understood a little bit about what was meant by living in the Spirit and merging with God. Mircea Eliade, the French, University of Chicago Professor of the History of Religions, in his classic The Sacred and Profane, calls the revelation of the sacred in ordinary objects, people and events an hierophany. In the state that this requires, “…all nature is capable of revealing itself as cosmic sacrality….” The entire world can become a hierophany with what Abraham Abulafia called an activated mind, the Jewish soul of emergent properties called the Nefesh. This entirely new world, Rudolf Otto in his 1917 Das Helige (The Sacred)