Find routes that are near home so you will be more inclined to head out for a run. If your running routes are far away, it may be challenging to stick with the plan. Connecting with local running stores might be a good idea - they can suggest you some local routes.
Try to run on flat surfaces whenever possible. Slanted areas, like the sides of roads, put uneven stress on your knees and other joints. If you develop lower leg pains, like shin splints, look for softer places to run like trails and grass. This will save your legs for race days when you have to hit the asphalt.
Your local high school is often a great place to go run. Most high-school tracks are open to the public. A standard high school track is a quarter mile, so it's easier to track the distance.
Keep your routine fresh by doing various routes and distances. Doing the same thing day after day results in boredom and giving up.
Try to avoid big roads with traffic lights. It will be safer and your runs won't be interrupted with red lights. If there are no other options and you have to hit the road, be sure to stay safe - wear bright or reflective gear, run facing traffic and avoid running with headphones.
Look for running trails in your area. They will be free of cars and likely have great scenery. Also remember that trail running can be fun and offer great views, but don't forget to take a bug spray with you.